Saiyami Kher made her debut in the Hindi film industry with the 2016 film Mirzya, directed by Rakeysh Omprakash Mehra. Post that, she has been appreciated for her performance in several noted films like Choked, Unpaused, Ghoomer, Sharmajee Ki Beti, and more.

There is a bit of Tahira Kashyap in all the five female leads of "Sharmajee Ki Beti", says the director about her first feature film, a passion project that she hopes will make audiences see women in a different light.